Littleton jumps route over the middle for pick-six

Watch the best plays by the Los Angeles Rams against the San Francisco 49ers in tonight's Week 15 win on Thursday Night Football.

Los Angeles Rams wide receiver Puka Nacua's best plays from his 108-yard game vs. the San Francisco 49ers in tonight's Week 15 win on Thursday Night Football.

Los Angeles Rams running back Kyren Williams' best plays from his 112-yard game vs. the San Francisco 49ers in Week 15 win on Thursday Night Football

Los Angeles Rams inside linebacker Christian Rozeboom calls the game with a sack on San Francisco 49ers quarterback Brock Purdy.

Los Angeles Rams cornerback Darious Williams intercepts San Francisco 49ers quarterback Brock Purdy's overthrown pass.

Los Angeles Rams quarterback Matthew Stafford connects with tight end Colby Parkinson for a gain of 14 yards against the San Francisco 49ers.

Los Angeles Rams quarterback Matthew Stafford launches a 51-yard pass to wide receiver Puka Nacua against the San Francisco 49ers.

Los Angeles Rams wide receiver Puka Nacua weaves through the San Francisco 49ers defense for a 13-yard first down.

Los Angeles Rams outside linebacker Byron Young engulfs San Francisco 49ers running back Isaac Guerendo on an authoritative tackle for a loss in the rain.

Los Angeles Rams defensive end Kobie Turner collects his second sack on San Francisco 49ers quarterback Brock Purdy for a 4-yard loss.

Los Angeles Rams running back Kyren Williams spins for a 10-yard gain against the San Francisco 49ers.

Los Angeles Rams defensive end Kobie Turner sacks San Francisco 49ers quarterback Brock Purdy for a 4-yard loss.

Los Angeles Rams wide receiver Puka Nacua with a 7-yard helmet-pinning catch on San Francisco 49ers cornerback Charvarius Ward.

Watch all of the Los Angeles Rams' top plays from their home win against the Buffalo Bills in Week 14 of the 2024 NFL regular season.

Watch Los Angeles Rams wide receiver Puka Nacua's Week 14 highlights against the Buffalo Bills as he caught 12 passes for 162 yards while adding 16 more yards on the ground in a 2-touchdown performance.

Check out Los Angeles Rams quarterback Matthew Stafford's best plays as he leads the team to a thrilling win against the Buffalo Bills in Week 14 of NFL action.

Los Angeles Rams wide receiver Puka Nacua's clutch second touchdown against Buffalo Bills boosts the team's lead to nine points in the fourth quarter.

Los Angeles Rams wide receiver Puka Nacua's eleventh catch of the day gets him up to the 143-yard mark against the Buffalo Bills.

Los Angeles Rams wide receiver Cooper Kupp involves leaps to snag in a touchdown grab against the Buffalo Bills.

Los Angeles Rams quarterback Matthew Stafford's 10th connection with wide receiver Puka Nacua gets the team to the Buffalo Bills' 24-yard line.

Los Angeles Rams running back Kyren Williams burns the Buffalo Bills defense for his second touchdown of the day.

Los Angeles Rams quarterback Matthew Stafford's 38-yard dime to wide receiver Cooper Kupp against the Buffalo Bills is one of the NFL's most accurate passes of 2024 regular season.

Los Angeles Rams quarterback Matthew Stafford's dime to wide receiver Puka Nacua against the Buffalo Bills has everyone in awe.

Los Angeles Rams rookie safety Kam Kinchens makes a touchdown-saving pass break-up on Buffalo Bills quarterback Josh Allen's heave downfield.

Los Angeles Rams wide receiver Puka Nacua toe-taps the sideline on an acrobatic over-the-shoulder grab against the Buffalo Bills.